Srna's talent was seen by many scouts in Croatia while he was young. He was later signed by Hajduk Split as his talent became desirable for the Croatian giants.[3] Come on Croatia At Hajduk, Srna won the 1999–2000 Croatian Cup, 2002–03 Croatian Cup and the 2000–01 Prva HNL. They played in the first round of 1999–2000 UEFA Cup, 2001–02 UEFA Cup, 2002–03 UEFA Cup, as well as the second round of the 2000–01 UEFA Champions League and the third round of the 2001–02 UEFA Champions League.Darijo Srna(Darijo in Persian : داریوش) (pronounced [dâːrio sř̩na]; born 1 May 1982) is a Croatian footballer who plays for Shakhtar Donetsk as a captain and is also the captain of the Croatian national team. He can play as a right back and at right midfield and is known for his crossing and freekick ability.[2]&nbsp

In 2003, Srna was sold, along with Stipe Pletikosa to Shakhtar Donetsk.[4] He is a common member and the captain in his club side, for whom he has made a large impact in the league.

After the 2006 World Cup, Benfica were reported to be after the player's signature but nothing materialized, with what many considered a fallen or rejected sale. Since then, he has been linked with a number of other clubs, including S.S. Lazio.

Srna made his debut in main stage of UEFA Champions League on 14 September 2004 against Milan.

On 20 May 2009, Srna won the UEFA Cup as captain of Shakhtar. Srna provided the assist for Jádson's winning goal seven minutes into extra time. This was the last UEFA Cup before the change to the Europa League.

Srna was named in the UEFA Champions League Team Of The Year according to player rater (statistics) in the 2010–2011 season where Shakhtar lost in the quarter-final to Barcelona. Srna gave 5 assists in 5 games[5]